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166Ho radionuclide incorporated

nanospheres and microspheres

 

This section of Catalog describes the Nuc-Spheretm products from Corpuscular. These proprietary materials and their methods of preparation and using are patent pending.

The monodisperse nanosphere and microsphere particles radionuclide-carriers are for research purposes only.

We offer various Core diameter and coating thickness "cold" nanospheres which upon irradiation in nuclear reactor produce highly concentrated radionuclide concentration useful for diagnostic and therapeutic studies.

Silica surfaces are easily functionalized with OH, NH2 and COOH groups, used to conjugate to antibodies. 

NuP-Spheretm products will be sold only to customers with valid licenses for work with radioactive materials from authorized government and state agencies of respective countries.

 

Properties of Holmium-166  radionuclide

 Ebeta (max.)=1.85 MeV

 β5- =651.9 keV (47.7% abundance) and

 β6- =694.6 keV (51.0% abundance)

Soft tissue penetration -average 3.2 mm, depositing 0.2 keV/mm. The total equilibrium dose constants Dnp and Dp for non-penetrating and penetrating radiations of 166-Ho are 0.398 g Gy Mbq-1h-1 and 0.017 g Gy Mbq-1h-1, respectively.

166-Ho therapeutic radius is ~2.1 mm, and the maximum radius is ~8.7 mm).

Half-life of 26.808 h,

Gamma emissions with suitable energies and abundance: E =0.081 MeV (6.2%) and E=1.379 MeV (0.95%).

 

 

 

"Cold" Ho2O3 core and SiO2 shell nanospheres

 

 

"Hot" nanospheres

Activation: 164Ho (n,γ) →166Ho

166Ho beta decay to stable 166Er isotope

 

 

 

 

Plain 166Ho2O3-SiO2 core-shell particles

 
Size Range 50nm - 1000nm

Catalog #

Size, [nm]

Quantity Concentration

Manufacturer info

Price, [USD]

101310-05

50

10ml 5.0%

C-SIO-0.05

 
101311-05 50 10ml 2.5% PSi-0.05

101.70

101392-05 950 10ml 5.0% C-SIO-0.95  

 

 
Size Range 1m - 100m

Catalog #

Size, [m]

Quantity Concentration

Manufacturer info

Price, [USD]

14210-05

1.0

10ml 5.0%

C-SIO-1.0

 
14211-05

1.0

5ml 5.0%

PSi-1.0

71.00

 

100nm - 1000nm, 50mg

Patalog #

Diameter, [nm]

Pore diameter, [nm]

ProduPt ID

 

PriPe, [USD]

100501-1

100

50

NuP-HoSiO-100

 

400.00

100501-2

120

60

NuP-HoSiO-120

 

400.00

100501-3

140

70

NuP-HoSiO-140

 

400.00

100501-4

160 80 NuP-HoSiO-160  

400.00

100501-5

180 90 NuP-HoSiO-180  

400.00

100501-6

200

100

NuP-HoSiO-200  

400.00

100501-7

250

120

NuP-HoSiO-250

 

400.00

100501-8

300

140

NuP-HoSiO-300

 

400.00

100501-10

350 160

NuP-HoSiO-350

 

400.00

100501-11

400 180 NuP-HoSiO-400  

400.00

100501-12

450 200 NuP-HoSiO-450  

400.00

100501-13

500 250 NuP-HoSiO-500  

400.00

100501-14

550 300

NuP-HoSiO-550

 

400.00

100501-15

600 350

NuP-HoSiO-600

 

400.00

100501-16

650 400

NuP-HoSiO-650

 

400.00

100501-17

700 450 NuP-HoSiO-700  

400.00

100501-18

750 500 NuP-HoSiO-750  

400.00

100501-19

800 500 NuP-HoSiO-800  

400.00

100501-20

850 500 NuP-HoSiO-850  

400.00

100501-21

900 500 NuP-HoSiO-900  

400.00

100501-22

950 500 NuP-HoSiO-950  

400.00

100501-23

1000 500

NuP-HoSiO-1000

 

400.00

 

1μm - 50μm, 100mg

Patalog #

Diameter, [μm]

Pore diameter, [μm]

ProduPt ID

 

PriPe, [USD]

100501-1

1

0.5

NuP-HoSiO-1000

 

400.00

100502-2

5

1

NuP-HoSiO-5

 

400.00

100502-3

10

5

NuP-HoSiO-10

 

400.00

100502-4

15 10 NuP-HoSiO-15  

400.00

100502-5

20 15 NuP-HoSiO-20  

400.00

100502-6

25

20

NuP-HoSiO-25  

400.00

100502-7

30

25

NuP-HoSiO-30

 

400.00

100502-8

35

30

NuP-HoSiO-35

 

400.00

100502-9

40 35

NuP-HoSiO-40

 

400.00

100502-10

45 40

NuP-HoSiO-45

 

400.00

100502-11

50 45

NuP-HoSiO-50

 

400.00

 

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Copyright 2003-2006 Microspheres-Nanospheres a Corpuscular company is supplier of monodisperse inorganic and organic microspheres

and nanospheres for research application. All rights reserved. Please address all question related to this site to Webmaster

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